Sulphadimethyloxazole ('nuprin') with streptomycin in the treatment of non-gonococcal urethritis.

The long-acting "sulfamoxole" has the advantage that fewer doses are required. Sulphonamides alone are not particularly successful in non-gonococcal urethritis (NGU). The best results have been obtained with the tetracyclines (with and without oleandomycin), and success rates of 81 -5 to 85 4 per cent. may be obtained (Willcox, 1958). A number of authors (e.g. Lyall, 1953; Jelinek, 1957; Prebble, 1957) have had significantly better results (e.g. success rates of 76 to 85 per cent.) when sulphonamides have been combined with a single injection of streptomycin. In a personal series of fifty cases using "Dosulfin"-a middle-acting mixed sulphonamide-plus streptomycin, 43 were followed and there were twelve failures-a success rate of 72-1 per cent. (Willcox, 1961). Such results, although